Protein Details: Aquaporin A

Protein ID

ICDB_Pro_1656

Protein Name

Aquaporin A

Gene Name

aqpA; DDB_G0267378

Organism

Dictyostelium discoideum (Social amoeba)

Length

279 amino acids

AlphaFoldDB

AF-Q9U8P7-F1-model_v4.pdb

Function

May form a water-specific channel (By similarity). Required for prolonged spore survival on fruiting bodies.

Sequence

MVKVVPLRFITYDPLKDPSKMIYRRPISKPVKAFKGFFSEFLGTLYLVYFCGGSVCAAFAVAGDSAARALLGGLIQGMALAALIWAVSGVSGCNLNPAVTLANLLSGRVGLIDSLYYVAAQILGCIAGAGILYGCLPNMYRIDLGVPHLAPGMNTGQAFLMEMMLTSILCLCVLGTSVFNVWDRRLNRIAPFAIGLALFIGVAIGFNFSGGALNPVRVLGPSIISGVWSHHWVYWLGPIVGAILAAFIYRCLLQERFDVIERPGYIAPLIDPSTAVSSY

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1016/s0378-1119(00)00201-8; 10.1038/nature03481

RefSeq

XP_647526.1